Alirio Melendez: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Sphingosine kinase signalling in immune cells: Potential as novel therapeutic targets

Alirio J. Melendez

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2008

Language:

english

File:

PDF, 809 KB

english, 2008

2

Sphingosine kinase signalling in immune cells

Tay Hwee Kee, Patricia Vit, Alirio J Melendez

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2005

Language:

english

File:

PDF, 122 KB

english, 2005

3

Allergy therapy: The therapeutic potential of targeting sphingosine kinase signalling in mast cells

Alirio J. Melendez

Journal:

European Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 198 KB

english, 2008

4

Retracted: Sphingosine kinase 1 regulates pro-inflammatory responses triggered by TNFα in primary human monocytes

Liang Zhi, Bernard P. Leung, Alirio J. Melendez

Journal:

Journal of Cellular Physiology

Year:

2006

Language:

english

File:

PDF, 216 KB

english, 2006

5

Neuronal apoptosis mediated by inhibition of intracellular cholesterol transport: Microarray and proteomics analyses in cultured murine cortical neurons

Chor Hui Vivien Koh, Zhao Feng Peng, Keli Ou, Alirio Melendez, Jayapal Manikandan, Robert Z. Qi, Nam Sang Cheung

Journal:

Journal of Cellular Physiology

Year:

2007

Language:

english

File:

PDF, 870 KB

english, 2007

6

Up-regulation of endoplasmic reticulum stress-related genes during the early phase of treatment of cultured cortical neurons by the proteasomal inhibitor lactacystin

Meng Shyan Choy, Minghui Jessica Chen, Jayapal Manikandan, Zhao Feng Peng, Andrew M. Jenner, Alirio J. Melendez, Nam Sang Cheung

Journal:

Journal of Cellular Physiology

Year:

2011

Language:

english

File:

PDF, 530 KB

english, 2011

7

Gene profiling reveals hydrogen sulphide recruits death signaling via the N-methyl-D-aspartate receptor identifying commonalities with excitotoxicity

Minghui Jessica Chen, Zhao Feng Peng, Jayapal Manikandan, Alirio J. Melendez, Gek San Tan, Ching Ming Chung, Qiu-Tian Li, Theresa M. Tan, Lih Wen Deng, Matthew Whiteman, Philip M. Beart, Phillip K. Mo

Journal:

Journal of Cellular Physiology

Year:

2011

Language:

english

File:

PDF, 460 KB

english, 2011

8

C-reactive protein-mediated phagocytosis and phospholipase D signalling through the high-affinity receptor for immunoglobulin G (FcγRI)

Katherine B. Bodman-Smith, Alirio J. Melendez, Ian Campbell, Patrick T. Harrison, Janet M. Allen, John G. Raynes

Journal:

Year:

2002

Language:

english

File:

PDF, 195 KB

english, 2002

9

SHORT INTEFERING RNA (siRNA) AS A NOVEL THERAPEUTIC

Peter N Pushparaj, Alirio J Melendez

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

10

INTRODUCTION

WS Fred Wong, Alirio J Melendez

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2006

Language:

english

File:

PDF, 43 KB

english, 2006

11

DNA MICROARRAY TECHNOLOGY FOR TARGET IDENTIFICATION AND VALIDATION

Manikandan Jayapal, Alirio J Melendez

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2006

Language:

english

File:

PDF, 186 KB

english, 2006

12

Proteasome inhibition by lactacystin in primary neuronal cells induces both potentially neuroprotective and pro-apoptotic transcriptional responses: a microarray analysis

Elaine Hau Jin Yew, Nam Sang Cheung, Meng Shyan Choy, Robert Z. Qi, Alan Yiu-Wah Lee, Zhao Feng Peng, Alirio J. Melendez, Jayapal Manikandan, Evelyn Siew-Chuan Koay, Lily-Lily Chiu, Wooi Loon Ng, Matt

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 402 KB

english, 2005

13

The helminth product ES-62 protects against septic shock via Toll-like receptor 4–dependent autophagosomal degradation of the adaptor MyD88

Puneet, Padmam, McGrath, Mairi A, Tay, Hwee Kee, Al-Riyami, Lamyaa, Rzepecka, Justyna, Moochhala, Shabbir M, Pervaiz, Shazib, Harnett, Margaret M, Harnett, William, Melendez, Alirio J

Journal:

Nature Immunology

Year:

2011

Language:

english

File:

PDF, 1.54 MB

english, 2011

14

Inhibition of FcεRI-mediated mast cell responses by ES-62, a product of parasitic filarial nematodes

Melendez, Alirio J, Harnett, Margaret M, Pushparaj, Peter N, Wong, WS Fred, Tay, Hwee Kee, McSharry, Charles P, Harnett, William

Journal:

Nature Medicine

Year:

2007

Language:

english

File:

PDF, 320 KB

english, 2007

15

Retraction: Sphingosine kinase 1 regulates pro-inflammatory responses triggered by TNFα in primary human monocytes

Liang Zhi, Bernard P. Leung, Alirio J. Melendez

Journal:

Journal of Cellular Physiology

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

16

U18666A-mediated apoptosis in cultured murine cortical neurons: Role of caspases, calpains and kinases

Chor Hui Vivien Koh, Robert Z. Qi, Dianbo Qu, Alirio Melendez, Jayapal Manikandan, Boon Huat Bay, Wei Duan, Nam Sang Cheung

Journal:

Cellular Signalling

Year:

2006

Language:

english

File:

PDF, 675 KB

english, 2006

17

OR.84. Role of Phospholipase D in T Cell Receptor Signalling Pathway Triggered by T Cell Receptor

Moizza Mansoor, Alirio Melendez

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

18

A global transcriptomic view of the multifaceted role of glutathione peroxidase-1 in cerebral ischemic–reperfusion injury

Minghui Jessica Chen, Connie H.Y. Wong, Zhao Feng Peng, Jayapal Manikandan, Alirio J. Melendez, Theresa M. Tan, Peter J. Crack, Nam Sang Cheung

Journal:

Free Radical Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 756 KB

english, 2011

19

Crosstalk between ARF6 and protein kinase Cα in FcγRI-mediated activation of phospholipase D1

Alirio J. Melendez, Margaret M. Harnett, Janet M. Allen

Journal:

Current Biology

Year:

2001

Language:

english

File:

PDF, 243 KB

english, 2001

20

A molecular switch changes the signalling pathway used by the FcγRI antibody receptor to mobilise calcium

Alirio Melendez, R.Andres Floto, Angus J. Cameron, David J. Gillooly, Margaret M. Harnett, Janet M. Allen

Journal:

Current Biology

Year:

1998

Language:

english

File:

PDF, 176 KB

english, 1998

21

Multifaceted role of nitric oxide in an in vitro mouse neuronal injury model: transcriptomic profiling defines the temporal recruitment of death signalling cascades

Zhao Feng Peng, Minghui Jessica Chen, Jayapal Manikandan, Alirio J. Melendez, Guanghou Shui, Françoise Russo-Marie, Matthew Whiteman, Philip M. Beart, Philip K. Moore, Nam Sang Cheung

Journal:

Journal of Cellular and Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 1.23 MB

english, 2012

22

Genome-wide gene expression profiling of human mast cells stimulated by IgE or FcεRI-aggregation reveals a complex network of genes involved in inflammatory responses

Manikandan Jayapal, Hwee Kee Tay, Renji Reghunathan, Liang Zhi, Kah Kiong Chow, Mary Rauff, Alirio J Melendez

Journal:

Year:

2006

Language:

english

File:

PDF, 558 KB

english, 2006

23

Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome

Renji Reghunathan, Manikandan Jayapal, Li-Yang Hsu, Hiok-Hee Chng, Dessmon Tai, Bernard P Leung, Alirio J Melendez

Journal:

Year:

2005

Language:

english

File:

PDF, 437 KB

english, 2005

24

Phospholipase D and immune receptor signalling

Alirio J. Melendez, Janet M. Allen

Journal:

Seminars in Immunology

Year:

2002

Language:

english

File:

PDF, 164 KB

english, 2002

25

Refining siRNA in vivo transfection: Silencing SPHK1reveals its key role in C5a-induced inflammation in vivo

Peter N. Pushparaj, Shiau Chen H’ng, Alirio J. Melendez

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2008

Language:

english

File:

PDF, 1.30 MB

english, 2008

26

Environmental toxicogenomics: A post-genomic approach to analysing biological responses to environmental toxins

Manikandan Jayapal, Rabindra N. Bhattacharjee, Alirio J. Melendez, M. Prakash Hande

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2010

Language:

english

File:

PDF, 708 KB

english, 2010

27

Temporal transcriptomic profiling reveals cellular targets that govern survival in HOCl-mediated neuronal apoptosis

Yann Wan Yap, Minghui Jessica Chen, Meng Shyan Choy, Zhao Feng Peng, Matthew Whiteman, Jayapal Manikandan, Alirio J. Melendez, Nam Sang Cheung

Journal:

Year:

2010

Language:

english

File:

PDF, 496 KB

english, 2010

28

Deciphering the mechanism of HNE-induced apoptosis in cultured murine cortical neurons: Transcriptional responses and cellular pathways

Zhao Feng Peng, Chor Hui Vivien Koh, Qiu Tian Li, Jayapal Manikandan, Alirio J. Melendez, Soon Yew Tang, Barry Halliwell, Nam Sang Cheung

Journal:

Neuropharmacology

Year:

2007

Language:

english

File:

PDF, 851 KB

english, 2007

29

Proteasome inhibition: An early or late event in nitric oxide-induced neuronal death?

Zhao Feng Peng, Minghui Jessica Chen, Yann Wan Yap, Jayapal Manikandan, Alirio J. Melendez, Meng Shyan Choy, Philip K. Moore, Nam Sang Cheung

Journal:

Year:

2008

Language:

english

File:

PDF, 1.19 MB

english, 2008

30

Human sphingosine kinase: molecular cloning, functional characterization and tissue distribution

Alirio J. Melendez, Estelle Carlos-Dias, Mark Gosink, Janet M. Allen, Laszlo Takacs

Journal:

Year:

2000

Language:

english

File:

PDF, 360 KB

english, 2000

31

The helminth product ES-62 protects against septic shock via Toll-like receptor 4–dependent autophagosomal degradation of the adaptor MyD88

Puneet, Padmam, McGrath, Mairi A, Tay, Hwee Kee, Al-Riyami, Lamyaa, Rzepecka, Justyna, Moochhala, Shabbir M, Pervaiz, Shazib, Harnett, Margaret M, Harnett, William, Melendez, Alirio J

Journal:

Nature Immunology

Year:

2011

Language:

english

File:

PDF, 75 KB

english, 2011

32

Retraction notice to “Refining siRNA in vivo transfection: Silencing SPHK1 reveals its key role in C5a-induced inflammation in vivo” [Int. J. Biochem. Cell Biol. 40 (2008) 1817–1825]

Pushparaj, Peter N., H’ng, Shiau Chen, Melendez, Alirio J.

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2013

Language:

english

File:

PDF, 133 KB

english, 2013

33

Retraction notice to “Environmental toxicogenomics: A post-genomic approach to analysing biological responses to environmental toxins” [Int. J. Biochem. Cell Biol. 42 (2010) 230–240]

Jayapal, Manikandan, Bhattacharjee, Rabindra N., Melendez, Alirio J., Hande, M. Prakash

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2013

Language:

english

File:

PDF, 173 KB

english, 2013

34

Aggregation of the Human High Affinity Immunoglobulin G Receptor (Fcγ RI) Activates both Tyrosine Kinase and G Protein-Coupled Phosphoinositide 3-Kinase Isoforms

Alirio J. Melendez, David J. Gillooly, Margaret M. Harnett and Janet M. Allen

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.67 MB

english, 1998

35

Synthesis and Evaluation of Sphingosine Analogues as Inhibitors of Sphingosine Kinases

Wong, Lingkai, Tan, Sheryl S. L., Lam, Yulin, Melendez, Alirio J.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 943 KB

english, 2009

36

FcγRI-triggered Generation of Arachidonic Acid and Eicosanoids Requires iPLA 2 but Not cPLA 2 in Human Monocytic Cells

Tay, Hwee Kee, Melendez, Alirio J.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 1.15 MB

english, 2004

37

REQUEST FOR RETRACTION: SHORT INTERFERING RNA (siRNA) AS A NOVEL THERAPEUTIC

Melendez-Romero, Alirio

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2013

Language:

english

File:

PDF, 95 KB

english, 2013

38

Phagocytosis: a repertoire of receptors and Ca2+ as a key second messenger

Melendez, Alirio J., Tay, Hwee Kee

Journal:

Bioscience Reports

Year:

2008

Language:

english

File:

PDF, 432 KB

english, 2008

39

New developments on the TNFα-mediated signalling pathways

Sethu, Swaminathan, Melendez, Alirio J.

Journal:

Bioscience Reports

Year:

2011

Language:

english

File:

PDF, 396 KB

english, 2011

40

Role of Cell Adhesion Molecules and Immune-Cell Migration in the Initiation, Onset and Development of Atherosclerosis

Chi, Zhang, Melendez, Alirio J.

Journal:

Cell Adhesion & Migration

Year:

2007

Language:

english

File:

PDF, 1.09 MB

english, 2007

41

Water and Ion Channels: Crucial in the Initiation and Progression of Apoptosis in Central Nervous System?

Chen, Minghui, Sepramaniam, Sugunavathi, Armugam, Arunmozhiarasi, Choy, Meng, Manikandan, Jayapal, Melendez, Alirio, Jeyaseelan, Kandiah, Cheung, Nam

Journal:

Current Neuropharmacology

Year:

2008

Language:

english

File:

PDF, 263 KB

english, 2008

42

Recent Trials for FTY720 (Fingolimod): A New Generation of Immunomodulators Structurally Similar to Sphingosine

Melendez, Alirio, Mansoor, Moizza

Journal:

Reviews on Recent Clinical Trials

Year:

2008

Language:

english

File:

PDF, 240 KB

english, 2008

43

Endocytosis and vesicular trafficking of immune complexes and activation of phospholipase D by the human high-affinity IgG receptor requires distinct phosphoinositide 3-kinase activities

GILLOOLY, David J., MELENDEZ, Alirio J., HOCKADAY, Austin R., HARNETT, Margaret M., ALLEN, Janet M.

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 275 KB

english, 1999

44

Endocytosis and vesicular trafficking of immune complexes and activation of phospholipase D by the human high-affinity IgG receptor requires distinct phosphoinositide 3-kinase activities

GILLOOLY, David J., MELENDEZ, Alirio J., HOCKADAY, Austin R., HARNETT, Margaret M., ALLEN, Janet M.

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 275 KB

english, 1999

45

FcγRI DIFFERENTIALLY ACTIVATES SEVERAL PKC ISOFORMS AND DIFFERENT PHOSPHOLIPASES DEPENDING ON MONOCYTE DIFFERENTIATION

Melendez, Alirio J., Harnett, Margaret M., Allen, Janet M.

Journal:

Biochemical Society Transactions

Year:

1999

Language:

english

File:

PDF, 116 KB

english, 1999

46

Advances in Antisense Oligonucleotide Development for Target Identification, Validation, and as Novel Therapeutics

Mansoor, Moizza, Melendez, Alirio J.

Journal:

Gene Regulation and Systems Biology

Year:

2008

Language:

english

File:

PDF, 308 KB

english, 2008

47

Genome activity profiling of monomeric-IgE and Fc-epsilon-RI-aggregation on human mast cells reveals a complex network of genes involved in inflammatory responses.

Manikandan, Jayapal, Melendez, Alirio Jose, Pushparaj, Peter Natesan

Journal:

Bioentrepreneur

Year:

2007

Language:

english

File:

PDF, 462 KB

english, 2007

48

Differences in the gene expression profile of human monocytic cells activated by high and low affinity Fc-gamma-receptors.

Manikandan, Jayapal, Reghunathan, Renji, Melendez, Alirio Jose, Pushparaj, Peter Natesan

Journal:

Bioentrepreneur

Year:

2007

Language:

english

File:

PDF, 328 KB

english, 2007

49

Differential Gene Expression of Human Mast cell Activation Reveals Gene profiles of Innate and Adaptive Immunity.

Manikandan, Jayapal, Renji, Reghunathan, Pushparaj, Peter Natesan, Melendez, Alirio Jose

Journal:

Bioentrepreneur

Year:

2007

Language:

english

File:

PDF, 258 KB

english, 2007

50

siRNA knockdown of SPHK1 in vivo protects mice from systemic, type-I Allergy.

Manikandan, Jayapal, Pushparaj, Peter Natesan, Melendez, Alirio Jose

Journal:

Bioentrepreneur

Year:

2007

Language:

english

File:

PDF, 324 KB

english, 2007